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Table 4 Synthesis, characterization methods, characteristics and antiplasmodial activity assessment of metal nanoparticles

From: A systematic review on anti-malarial drug discovery and antiplasmodial potential of green synthesis mediated metal nanoparticles: overview, challenges and future perspectives

Items Parameters Categories References
Mode of preparation Part used for NPs synthesis Leaves [47,48,49,50, 52, 53, 57,58,59,60]
Flowers [53]
Seeds [55, 56, 60]
Barks [57]
Whole organism [61,62,63]
Extraction solvent Water [47, 48, 50,51,52,53,54,55,56,57,58,59,60]
Tris–HCl buffer [49]
Main method of preparation Washing, cutting, boiling, decantation, filtration [47,48,49,50,51,52,53,54,55,56, 59]
Physico-chemical characterization of NPs Plasmon resonance UV–Vis [47, 48, 50,51,52,53,54,55,56,57,58,59,60,61,62,63]
Shape, size and size distribution FESEM/SEM, EDX, EDAX [47, 48, 50,51,52,53,54,55,56, 60,61,62,63]
HRTEM/TEM, SAED [49, 51, 57,58,59,60,61, 63]
Silver content AAS [49]
Interface NPs-metabolites FTIR [49, 51,52,53, 55,56,57, 59, 60, 62, 63]
Size distribution DLS [49, 59]
Structure-crystallinity XRD [47,48,49,50,51,52,53,54,55,56,57, 61]
Stability Zeta potential [47, 51, 53, 55]
Characteristics of NPs Metal source AgNO3 [47,48,49,50, 52, 54,55,56,57,58, 61, 63]
HAuCl4 [53, 57, 60, 61]
Pd(OAc)2 [51]
TiCl4 [59]
Time of production < 30 min [50, 58, 59, 61]
> 30 min [47, 49, 51, 53,54,55,56]
Shape Spherical or mainly spherical [47,48,49,50,51, 54, 56,57,58,59, 62]
Other shapes (cubical, polygonal, triangular, oval, ellipsoidal, rectangular) [50,51,52,53, 55, 57,58,59, 61]
NPs aggregation phenomenon Yes [49, 56]
  1. AAS atomic absorption spectroscopy, DLS dynamic light scattering, DRIFT diffuse reflectance infrared Fourier transform, EDS Electron Diffraction Spectrophotometer, FESEM field emission scanning electron microscopy, FTIR Fourier-transform infrared, HR-TEM high resolution transmission electron microscopy, SAED size and elected area diffraction, SEM scanning electron microscopy, TEM transmission electron microscopy, EDAX energy dispersive X-ray, HF health facility