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Table 2 Description of Plasmodium falciparum infected and uninfected study participants (defined by qPCR)

From: Changing plasma cytokine, chemokine and growth factor profiles upon differing malaria transmission intensities

 

Infected (by qPCR)

Uninfected (by qPCR)

2010

2013

p-value

2010

2013

p-value

N

96

65

 

138

78

 

Age [median (IQR)]

9.79 (3.61–35.89)

10.06 (3.31–27.64)

0.462

28.4 (5.86–64.03)

7.18 (3.28–36.38)

0.002

Age group (%)

  

0.737

  

0.016

 < 2 years

8 (8.3)

10 (15.4)

15 (10.9)

14 (17.9)

 2–5 years

29 (30.2)

16 (24.6)

15 (10.9)

15 (19.2)

 5–10 years

12 (12.5)

6 (9.2)

15 (10.9)

14 (17.9)

 10–20 years

15 (15.6)

12 (18.5)

0 (0.0)

1 (1.3)

 20–60 years

23 (24.0)

16 (24.6)

45 (32.6)

18 (23.1)

 > 60 years

9 (9.4)

5 (7.7)

48 (34.8)

16 (20.5)

Male (%)

42 (43.8)

31 (47.7)

0.632

49 (35.5)

33 (42.3)

0.381

Anaemia (%)

47 (49.0)

28 (43.1)

0.521

79 (57.2)

39 (50.0)

0.322

Area (%)

  

0.002

  

< 0.001

 Ilha Josina

19 (19.8)

19 (29.2)

23 (16.7)

4 (5.1)

 Malavele

7 (7.3)

9 (13.8)

12 (8.7)

11 (14.1)

 Manhiça

26 (27.1)

11 (16.9)

45 (32.6)

25 (32.1)

 Maragra

30 (31.2)

6 (9.2)

51 (37.0)

15 (19.2)

 Palmeira

11 (11.5)

16 (24.6)

4 (2.9)

17 (21.8)

 Taninga

3 (3.1)

4 (6.2)

3 (2.2)

6 (7.7)

Par. dens. qPCR (parasites/µL) [median (IQR)]

10.46 (1.61–102.94)

7.61 (1.43–299.84)

0.999

NA

NA

Clinical malaria (%)

  

0.026

NA

NA

 No

93 (96.9)

55 (84.6)

 Yes

3 (3.1)

8 (12.3)

 NA

0 (0.0)

2 (3.1)

  1. Continuous variables were analysed using the non-parametric Wilcoxon rank-sum test. Comparisons between groups for categorical variables were done using Fisher’s exact test. Parasite densities were log10 transformed