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Table 3 Schizont maturation inhibition (%) and haemolysis of normal erythrocytes (%) with effect to the chalcones

From: In vitro anti-malarial efficacy of chalcones: cytotoxicity profile, mechanism of action and their effect on erythrocytes

Drugs/compound% Schizont maturation inhibition ± SD (MRC-2) (Conc. = 6.25 μg/mL)% Schizont maturation inhibition ± SD (RKL-9) (Conc. = 6.25 μg/mL)% Hemolysis ± SD (Conc. = 12.5 μg/mL)
182.43 ± 20.5149.66 ± 25.461.44 ± 0.005
271.76 ± 10.6158.02 ± 21.210.86 ± 0.002
359.26 ± 4.9563.71 ± 2.831.01 ± 0.003
447.48 ± 17.6857.69 ± 7.780.94 ± 0.006
558.65 ± 7.7840 ± 20.510.65 ± 0.001
651.05 ± 42.4243.85 ± 33.231.15 ± 0.005
794.24 ± 2.2185.82 ± 6.361.08 ± 0.001
875.17 ± 12.0277.78 ± 1.410.83 ± 0.003
950.32 ± 33.2348.87 ± 25.461.30 ± 0.009
1064.44 ± 9.9049.62 ± 19.791.51 ± 0.013
CHL88.39 ± 0.710.86 ± 0.001
QNN71.87 ± 16.262.16 ± 0.035
ART (ng/mL)87.88 ± 2.121.94 ± 0.026
  1. CHL chloroquine, QNN quinine hydrochloride, ART artemisinin