Table 2 Antibody response against PvAMA-1 at three sites in India
Seroprevalence | Chennai | Nadiad | Rourkela | Total | ||||
|---|---|---|---|---|---|---|---|---|
n/N (%) | 95% CI | n/N (%) | 95% CI | n/N (%) | 95% CI | n/N (%) | 95% CI | |
Overall | 31/66 (47.0) | 35.0–59.3 | 43/92 (46.7) | 36.6–57.1 | 21/76 (27.6) | 18.6 –39.0 | 95/234 (40.6) | 34.4–47.1 |
Gender | ||||||||
 Male | 23/41 (56.1) | 40.2–70.9 | 25/60 (41.7) | 29.6–54.8 | 10/45 (22.2) | 12.1–37.2 | 58/146 (39.7) | 32.0–48.0 |
 Female | 8/25 (32.0) | 16.0–53.7 | 18/32 (56.2) | 38.1–72.9 | 11/31 (35.5) | 20.1–54.5 | 37/88 (42.0) | 32.0–52.7 |
Age (years) | ||||||||
 < 15 | 0 | 0 | 7/20 (35.0) | 16.4–59.6 | 3/25 (12.0) | 03.6–33.3 | 10/45 (22.2) | 12.1–37.2 |
 ≥ 15 | 31/66 (47.0) | 35.0–59.3 | 36/72 (50.0) | 38.4–61.6 | 18/51 (35.3) | 23.1 –49.7 | 85/189 (45.0) | 38.0–52.2 |
PCR | ||||||||
 Positive | 23/37 (62.2) | 45.0 –76.7 | 39/49 (79.6) | 65.5–88.9 | 13/28 (46.4) | 28.2–65.7 | 75/114 (65.8) | 56.5–74.0 |
 Negative | 8/29 (27.6) | 13.1–47.5 | 4/43 (9.3) | 03.4–23.0 | 8/48 (16.7) | 08.3–30.5 | 20/120 (16.7) | 10.9–24.5 |
Malaria | ||||||||
 Asymptomatic | 18/28 (64.3) | 44.1–80.4 | 21/27 (77.8) | 57.0–90.2 | 11/25 (44.0) | 25.2–64.7 | 50/80 (62.5) | 51.2–72.6 |
 Symptomatic | 5/9 (55.5) | 19.5–86.6 | 18/22 (81.8) | 58.1–93.6 | 2/3 (66.7) | 0.3–99.9 | 25/34 (73.5) | 55.4–86.1 |
Parasitaemia | ||||||||
 Low | 19/25 (76.0) | 54.1–89.5 | 28/35 (80.0) | 62.6–90.5 | 5/10 (50.0) | 18.1–81.9 | 52/70 (74.3) | 62.5–83.3 |
 High | 3/4 (75.0) | 4.1–99.5 | 11/13 (84.6) | 49.0–96.9 | 4/7 (57.1) | 15.0–90.9 | 18/24 (75.0) | 52.5–89.0 |