Table 5 Predicted CD8 + T-cell, CD4 + T-cell, and B-cell epitopes in PfRH5 (IC50 < 50 nM)
Allele | Predicted peptide | IC50 | Number of polymorphic sites |
|---|---|---|---|
T-cell epitopes | |||
 Class II | |||
  DRB1_1304 | LNTNVNDAL | 8.72 | 0 |
TNVNDALKY | 30.21 | 0 | |
  DRB1_0701 | YLFIPSHNS | 12.81 | 0 |
FKELSNYNI | 27.83 | 0 | |
YNIANSIDI | 46.31 | 0 | |
YKHLYSNCI | 47.83 | 0 | |
YIAVDAFIK | 48.32 | 1 | |
  DRB1_1101 | LTLLTIQST | 21.37 | 0 |
IKSYLNTNV | 41.22 | 0 | |
FIKKYSVFN | 44.67 | 0 | |
FNQINDGML | 48.35 | 0 | |
FKELSNYNI | 48.56 | 0 | |
YGKYIAVDA | 48.64 | 1 | |
  DRB1_0120 | FNQINDGML | 31.84 | 0 |
YNIANSIDI | 37.21 | 0 | |
LKYLFIPSH | 45.57 | 0 | |
YKHLYSNCI | 47.87 | 0 | |
 Class I | |||
  HLA-A*30:01 | KTKNQENNL | 14.79 | 0 |
IAVDAFIKK | 15.87 | 0 | |
KVKSKTNET | 36.71 | 0 | |
SVIIPHYTF | 29.00 | 0 | |
  HLA-B*35:01 | PHYTFLDY | 15.36 | 0 |
FIKKINETY | 40.42 | 0 | |
B-cell epitope | PSHNSFIKKYSV | 0 | Â |