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Table 2 Association of maternal age, parity status, ANC clinic characteristics and adverse pregnancy outcomes by number of IPTp-SP doses

From: Coverage and effectiveness of intermittent preventive treatment in pregnancy with sulfadoxine–pyrimethamine (IPTp-SP) on adverse pregnancy outcomes in the Mount Cameroon area, South West Cameroon

Variables

Categories

Doses [% (n)]

p-value$

≤ 1

2

≥ 3

Age group (years)

< 21

24.4 (22)

18.0 (27)

20.2 (41)

0.853

21–25

28.6 (32)

30.0 (45)

33 (67)

> 25

51.8 (58)

52.0 (78)

46.8 (95)

Parity

Primiparae

27.7 (31)

31.3 (47)

30.0 (61)

0.128

Secundiparae

20.5 (23)

30.0 (45)

31.5 (64)

Multiparae

51.8 (58)

38.7 (58)

38.4 (78)

Trimester of first ANC visit

First

5.5 (6)

4.7 (7)

9.9 (20)

< 0.001

Second

53.2 (58)

70.7 (106)

86.2 (175)

Third

41.3 (45)

24.7 (37)

3.9 (8)

Number of ANC visits

< 4 visits

70.5 (79)

45.3 (68)

16.7 (34)

< 0.001

ITN Usage

Yes

58.9 (66)

64.0 (96)

75.4 (153)

0.006

PM infection

Positive

14.3 (16)

17.3 (26)

21.7 (44)

0.245

Anaemia status*

Anaemic

72.2 (70)

63.6 (89)

59.2 (106)

0.102

Birth weight status*

LBW

13.5 (13)

4.3 (6)

4.4 (8)

0.006

GMPMD (range)

a1.1 (0.1–63.4) (16)

b0.9 (0.1–68) (25)

c1.3 (0.1–100) (42)

0.160

Mean Hb levels*

a10.0 ± 1.5

(97)

b10.5 ± 1.3 (140)

c10.5 ± 1.4

(179)

0.015

Mean birth weight*

a3.1 ± 0.6

(96)

b 3.3 ± 0.5 (140)

c3.4 ± 0.5

(180)

< 0.001

  1. * Analysis excludes 48 women resident in Munyenge and positive for Schistosoma haematobium infection
  2. $Values from Pearson Chi square test (categorical variables) and ANOVA and Post hoc test (continuous variables); ANC antenatal clinic, ITN insecticide-treated nets, PM placental malaria, GMPMD geometric mean placenta parasite density, Hb haemoglobin
  3. Significant difference between b vs a: Hb; p = 0.035
  4. Significant difference between c vs a: Hb; p = 0.011
  5. Significant difference between b vs a: BWT; p = 0.021
  6. Significant difference between c vs a: BWT; p < 0.001
  7. No significant difference in Hb and BWT between c and b (p = 1.000)