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Table 4 Comparison of ID50 for AB311 and AB317 in protection from parasitaemia assay

From: Characterization of two in vivo challenge models to measure functional activity of monoclonal antibodies to Plasmodium falciparum circumsporozoite protein

StudyAB311 (μg)AB317 (μg)RatioP value
1341 (228, 455)205 (119, 290)1.70.07
2304 (239, 369)170 (*)1.80.46
3305 (229, 381)295 (221, 368)1.00.44
Pooled320 (270, 371)227 (178, 277)1.40.02
  1. ID50 was estimated in three studies and a pooled group with data from all three studies using 2PL analysis. * 2PL method could not estimate confidence intervals for this experiment