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Table 2 Prevalence of K76T mutation per study site

From: Molecular surveillance of anti-malarial drug resistance in Democratic Republic of Congo: high variability of chloroquinoresistance and lack of amodiaquinoresistance

Site

Positive RDT/thick blood sample

N

Positive Pf PCR

N (%)

Samples successfully sequenced among positive Pf PCR

N

Samples with K76T mutant

N

Prevalence of K76T mutation % (95% CI)

Bolenge

98

73 (74.5)

56

18

32.1 (20.3–46.6)

Fungurume

92

65 (70.7)

65

1

1.5 (0.0–8.3)

Kalima

97

67 (69.1)

66

3

4.5 (0.9–12.7)

Kamina

98

73 (74.5)

71

8

11.3 (5.0–21.0)

Karawa

97

66 (68.0)

54

6

11.1 (4.2–22.6)

Katana

105

78 (74.3)

76

68

89.5 (80.3–95.3)

Kinshasa

160

160 (100)

160

78

48.8 (40.8–56.8)

Kisangani

128

93 (72.7)

85

4

4.7 (1.3–11.6)

Lubumbashi

101

56 (55.4)

56

1

1.8 (0.0–9.6)

Vanga

94

75 (79.8)

75

31

41.3 (30.1–53.3)

Total

1070

806 (75.3)

764

218

28.5 (25.4–31.9)

  1. N number; globally, there was a significant difference of K76T prevalence between sites (p < 0.001)