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Table 4 Performance of uRDT and cRDT against qPCR. RECIPAL study, 2014–2017

From: Prevalence and clinical impact of malaria infections detected with a highly sensitive HRP2 rapid diagnostic test in Beninese pregnant women

  PCR Value (95%CI)a
(+) (−) Total Sensitivityb Specificityb PPV NPV Positive LR Negative LR
cRDT
 (+) 76 33 109 44.2% 95.7% 69.7% 88.5% 10.3 0.6
 (−) 96 737 833 (36.6–51.9) (94.0–97.0) (60.2–78.2) (86.2–90.6) (7.1–15) (0.5–0.7)
uRDT
 (+) 104 49 153 60.5% 93.6% 68.0% 91.4% 9.5 0.4
 (−) 68 721 789 (52.7–67.8) (91.7–95.3) (60.0–75.3) (89.2–93.2) (7.1–12.8) (0.3–0.5)
  1. PPV Predictive Positive Value, NPV Negative Predictive Value, LR Likelihood Ratio
  2. aFor all performance characteristics, exact binomial confidence intervals were computed
  3. bP-value < 0.05 using McNemar test for matched pairs