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Table 6 HRP2 concentration and parasite density according to qPCR, uRDT and cRDT positivity. RECIPAL study, 2014–2017

From: Prevalence and clinical impact of malaria infections detected with a highly sensitive HRP2 rapid diagnostic test in Beninese pregnant women

  qPCR positive qPCR negative
N HRP2 positive Mean HRP2 (pg/mL)b 95%CI Mean qPCR density (parasites/µL) b 95%CI N HRP2 positive Mean HRP2 (pg/mL)b 95%CI
cRDT and uRDT positive 76 76 27,911 16,791–46,395 532 324–874 31 31c 16,881 5597 –50,914
cRDT negative and uRDT positive 28 28 1049 757–1,455 20.7 10.8 –39.6 18 17c 616 427–890
cRDT and uRDT negative 68 28 191 157–233 17 9 –30 718 58 160 135– 189
  1. aOut of 721 qPCR-negative specimens, 3 were not included in the Table 2 of them were cRDT-positive and uRDT-negative; and one (RDTs-negative) was not tested for HRP2
  2. bGeometric mean (95% confidence interval); HRP2 concentration and parasite density by qPCR calculated in positive HRP2 (qPCR) specimens
  3. cAmong the women at delivery who were qPCR negative in peripheral blood, but positive by uRDT and had detectable levels of HRP2, all of them (5/5) were negative by qPCR in placental blood