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Table 7 Association between malaria and maternal and child outcomes (maternal anaemia during pregnancy and low birthweight)

From: Prevalence and clinical impact of malaria infections detected with a highly sensitive HRP2 rapid diagnostic test in Beninese pregnant women

 

Maternal anaemiaa

Low birthweightb

AOR

95%CI

P value

AOR

95%CI

P value

Malariac

 Group 1–No infection

Ref

  

Ref

  

 Group 2–qPCR infection

1.59

0.76–3.45

0.24

1

NA

 

 Group 3–uRDT infection

3.44

1.29–9.19

0.01

5.27

0.46; 57.14

0.17

 Group 4–cRDT infection

2.03

1.01-4.01

0.05

2.29

0.57; 9.17

0.24

Gravidity

 Primi-secundigravidae

Ref

  

Ref

  

 Multigravidae

0.64

0.34–1.21

0.17

0.54

0.15; 1.88

0.33

Trimester of pregnancy

 1st trimester

Ref

     

 3rd trimester

3.76

2.30–6.13

< 10−3

   

Ethnicityd

2.78

1.48–5.23

0.002

  1. RECIPAL, 2014–2017
  2. NA not applicable
  3. aMaternal anaemia (Hb level < 11 g/dL) in the 1st or 3rd trimester of pregnancy. Final logistic mixed regression model adjusted for gravidity, ethnicity and trimester of pregnancy (n = 559 observations, 319 women); aOR: adjusted Odd’s ratio
  4. bLow birthweight (< 2500 grams), twins and stillbirths excluded. Final logistic regression model adjusted for gravidity (n = 175)
  5. cMalaria status (1) at the time of Hb level determination in the 1st and 3rd trimesters of pregnancy or (2) at delivery based on diagnostic tests positivity in maternal peripheral and placental blood. Women were classified according to the highest group to which they belonged in either peripheral or placental blood (e.g. women classified in group 3 based on peripheral blood and in group 4 based on placental blood were at the end classified in group (4); Groups 1 to 4 defined as described in Table 1
  6. dEthnicity: Toffin (considered as the reference) vs. others