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Table 7 Association between malaria and maternal and child outcomes (maternal anaemia during pregnancy and low birthweight)

From: Prevalence and clinical impact of malaria infections detected with a highly sensitive HRP2 rapid diagnostic test in Beninese pregnant women

  Maternal anaemiaa Low birthweightb
AOR 95%CI P value AOR 95%CI P value
Malariac
 Group 1–No infection Ref    Ref   
 Group 2–qPCR infection 1.59 0.76–3.45 0.24 1 NA  
 Group 3–uRDT infection 3.44 1.29–9.19 0.01 5.27 0.46; 57.14 0.17
 Group 4–cRDT infection 2.03 1.01-4.01 0.05 2.29 0.57; 9.17 0.24
Gravidity
 Primi-secundigravidae Ref    Ref   
 Multigravidae 0.64 0.34–1.21 0.17 0.54 0.15; 1.88 0.33
Trimester of pregnancy
 1st trimester Ref      
 3rd trimester 3.76 2.30–6.13 < 10−3    
Ethnicityd 2.78 1.48–5.23 0.002
  1. RECIPAL, 2014–2017
  2. NA not applicable
  3. aMaternal anaemia (Hb level < 11 g/dL) in the 1st or 3rd trimester of pregnancy. Final logistic mixed regression model adjusted for gravidity, ethnicity and trimester of pregnancy (n = 559 observations, 319 women); aOR: adjusted Odd’s ratio
  4. bLow birthweight (< 2500 grams), twins and stillbirths excluded. Final logistic regression model adjusted for gravidity (n = 175)
  5. cMalaria status (1) at the time of Hb level determination in the 1st and 3rd trimesters of pregnancy or (2) at delivery based on diagnostic tests positivity in maternal peripheral and placental blood. Women were classified according to the highest group to which they belonged in either peripheral or placental blood (e.g. women classified in group 3 based on peripheral blood and in group 4 based on placental blood were at the end classified in group (4); Groups 1 to 4 defined as described in Table 1
  6. dEthnicity: Toffin (considered as the reference) vs. others