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Table 1 Frequency of genotyping success in samples collected on filter-paper versus rapid diagnostic tests

From: Stable high frequencies of sulfadoxine–pyrimethamine resistance associated mutations and absence of K13 mutations in Plasmodium falciparum 3 and 4 years after the introduction of artesunate plus sulfadoxine–pyrimethamine in Ujjain, Madhya Pradesh, India

 

Number (percent) of samples with successful genotyping

Fisher’s exact p value comparing filter-paper and RDT extracted samples

All samples (n = 127)

Filter-paper samples (n = 92)

Rapid diagnostic tests (n = 35)

Pfcrt K76T

102 (80%)

87 (95%)

15 (43%)

< 0.001

Pfmdr1 N86Y

115 (91%)

89 (97%)

26 (74%)

< 0.001

Pfdhfr seq

87 (69%)

81 (88%)

6 (17%)

< 0.001

Pfdhps seq

89 (70%)

82 (89%)

7 (20%)

< 0.001

Pfdhfr seq or RFLP 108

104 (82%)

84 (91%)

20 (57%)

< 0.001

Pfdhps seq or RFLP 436, 437, 540

105 (83%)

84 (91%)

21 (60%)

< 0.001

K13

87 (69%)

73 (79%)

14 (40%)

< 0.001