Drugs | West Africa | Central Africa | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Wild type I356 | Mutant 356T | p value | Wild type I356 | Mutant 356T | p value | |||||
Median (no) | Min-Max | Median (no) | Min-Max | Median (no) | Min–Max | Median (no) | Min–Max | |||
PPQ | 22.2 (49) | 6.8–76.3 | 19.9 (66) | 1.2–544 | 0.32 | 24.5 (36) | 4.1–79 | 21.4 (70) | 0.67–96.3 | 0.4 |
QN | 69.1 (49) | 11.7–906.3 | 162.6 (68) | 6.2–590.5 | 0.001 | 98.2 (36) | 17.6–365.2 | 183.4 (73) | 28.9–538.4 | 0.02 |
MQ | 30.4 (49) | 2.9–89.8 | 22.4 (67) | 0.8–100.6 | 0.01 | 33.3 (38) | 0.7–97.9 | 21.5 (72) | 0.62–133.9 | 0.04 |
CQ | 37.4 (49) | 6.2–283.2 | 26.5 (68) | 5.5–359.5 | 0.1 | 42.8 (39) | 4.1–474.2 | 26.9 (73) | 5.79–325 | 0.01 |
LMF | 3.0 (49) | 0.5–61.54 | 4.0 (68) | 0.6–18.2 | 0.6 | 2.8 (40) | 0.6–15.5 | 3.6 (73) | 0.55–22.4 | 0.5 |
DQ | 19.2 (49) | 3.4–169.2 | 27.1 (68) | 2.5–185.1 | 0.07 | 22.8 (40) | 5.1–152.8 | 20.8 (73) | 4.7–152.9 | 0.4 |
PND | 8.8 (48) | 1.2–50.1 | 14.5 (66) | 0.7–119.3 | 0.005 | 11.1 (38) | 3.9–41 | 12.3 (67) | 0.2–47.9 | 0.8 |
DHA | 2.9 (49) | 0.4–8.3 | 3.1 (68) | 0.2–12.8 | 0.9 | 3.5 (40) | 0.7–7.7 | 2.1 (73) | 0.47–11.1 | 0.08 |
AS | 1.8 (49) | 0.4–15.48 | 1.8 (67) | 0.2–9.8 | 0.6 | 2.5 (39 | 0.6–5.7 | 1.7 (71) | 0.29–30.2 | 0.05 |