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Table 1 Genetic diversity and natural selection test and recombination analysis of global PfCSP C-terminus

From: Genetic polymorphism of Plasmodium falciparum circumsporozoite protein on Bioko Island, Equatorial Guinea and global comparative analysis

 

S

H

Hd ± SD

dN-dS

Tajima’D

Fu and Li’s D

Fu and Li’s F

Ra

Rb

Rm

Bioko island

33

34

0.962 ± 0.008

0.0166

− 0.68556

− 1.23926

− 1.22255

0.0888

32.1

8

Cameroon

12

7

0.944 ± 0.70

0.037

− 0.84239

− 0.68964

− 0.81319

0.0919

15.9

2

Gambia

23

21

0.921 ± 0.022

0.0182

0.13689

0.31057

0.29579

0.057

21.5

6

Ghana

37

89

0.960 ± 0.004

0.0194

− 0.48482

0.03757

− 0.23777

0.0897

33.8

7

Senegal

31

42

0.954 ± 0.008

0.0193

− 0.15853

0.44100

0.23957

0.0992

37.4

6

Tanzania

21

29

0.966 ± 0.009

0.059

0.60634

0.80724

0.875

0.1838

31.8

6

Congo

22

25

0.947 ± 0.011

0.0175

0.18825

0.17445

0.21407

0.0666

25.1

6

Nigeria

7

4

0.900 ± 0.161

− 0.194

0.13160

0.78960

0.69173

0.1954

33.8

0

Mali

23

26

0.947 ± 0.014

0.0192

0.16275

0.90715

0.76259

0.1069

40.3

5

Malawi

28

51

0.965 ± 0.004

0.0189

0.26223

0.56701

0.52963

0.0883

33.3

9

Guinea

23

26

0.955 ± 0.011

0.0185

0.08885

1.17263

0.93102

0.1271

47.9

5

India

2

2

0.389 ± 0.164

0.0057

0.19590

1.063

0.94854

0.0006

0.1

0

Iran

2

2

0.467 ± 0.075

0.0068

1.56386

0.85807

1.20551

0.0127

2.2

0

Myanmar

7

7

0.342 ± 0.080

0.0021

− 1.06145

0.43133

− 0.06134

0

0.001

1

Philippines

18

9

0.821 ± 0.041

0.073

1.01981

1.64995*

1.70088*

0.0977

16.9

1

Thailand

13

9

0.535 ± 0.048

0.0066

− 0.16926

0.24690

0.11276

0

0.001

4

Vietnam

18

11

0.757 ± 0.034

0.0122

− 0.03642

0.81913

0.60286

0.009

3.4

3

Bangladesh

20

14

0.890 ± 0.036

0.0134

− 0.53740

− 0.45410

− 0.56526

0.0549

20.7

5

Cambodia

22

22

0.812 ± 0.009

0.0115

0.10655

1.81010*

1.33256

0.0231

8.7

6

Laos

18

10

0.813 ± 0.030

0.0108

− 0.13493

1.27356

0.91834

0.0154

5.8

3

Brazil

8

3

0.459 ± 0.080

0.032

0.72190

1.30884

1.31767

0

0.001

0

Venezuela

14

7

0.911 ± 0.077

0.023

0.64552

0.79924

0.85743

0.167

28.9

2

PNG

5

4

0.532 ± 0.034

0.02

0.41918

− 0.01266

0.15105

0.0283

4.9

1

Solomon

4

3

0.405 ± 0.069

0.031

− 0.00704

1.00249

0.80842

0

0.004

0

Vanuatu

2

2

0.276 ± 0.046

0.016

0.70558

0.67407

0.80111

0

0.001

0

  1. n: number of samples; S: segregating sites; H: number of haplotypes; Hd: haplotype diversity; dN: the number of synonymous substitutions per site; dS: the number of nun-synonymous substitutions per site; Ra: estimate of recombination between adjacent sites; Rb: estimate of recombination per gene; Rm: minimum number of recombination events; *p < 0.05