Table 1 Signalling pathways and genes in Mouse Signal Transduction Pathway Finder PCR Array
Signalling pathways | Genes |
|---|---|
TGFß pathway | Atf4, Cdkn1b (p27Kip1), Emp1, Gadd45b, Herpud1, Ifrd1, Myc, Tnfsf10 |
WNT pathway | Axin2, Ccnd1, Ccnd2, Dab2, Fosl1 (Fra-1), Mmp7 (Matrilysin), Myc, Ppard, Wisp1 |
NFκB pathway | Bcl2a1a (Bfl-1/A1), Bcl2l1 (Bcl-x), Birc3 (c-IAP1), Ccl5 (Rantes), Csf1 (Mcsf), Icam1, Ifng, Stat1, Tnf |
JAK/STAT pathway JAK1, 2/STAT1 STAT3 STAT5 JAK1, 3/STAT6 | Irf1 Bcl2l1 (Bcl-x), Ccnd1, Cebpd, Lrg1, Mcl1, Socs3 Bcl2l1 (Bcl-x), Ccnd1, Socs3 Fcer2a, Gata3 |
p53 pathway | Bax, Bbc3, Btg2, Cdkn1a (p21Cip1/Waf1), Egfr, Fas (Tnfrsf6), Gadd45a, Pcna, Rb1 |
Notch pathway | Hes1, Hes5, Hey1, Hey2, Heyl, Id1, Jag1, Lfng, Notch1 |
Hedgehog pathway | Bcl2, Bmp2, Bmp4, Ptch1, Wnt1, Wnt2b, Wnt3a, Wnt5a, Wnt6 |
PPAR pathway | Acsl3, Acsl4, Acsl5, Cpt2, Fabp1, Olr1, Slc27a4, Sorbs1 |
Oxidative stress | Fth1, Gclc, Gclm, Gsr, Hmox1, Nqo1, Sqstm1, Txn1, Txnrd1 |
Hypoxia | Adm, Arnt, Car9, Epo, Hmox1, Ldha, Serpine1 (PAI-1), Slc2a1, Vegfa |