Skip to main content

Table 1 Molecular genotyping of in vitro parasite samples

From: Piperaquine resistant Cambodian Plasmodium falciparum clinical isolates: in vitro genotypic and phenotypic characterization

Sample ID

pfmdr1

CN

K13

C580Y

pfpm2

CN

Exo

E415G

PfCRT

Group

T93S

H97Y

F145I

I218F

M343L

C350R

G353V

1

0.72

Y

2.85

G

T

Y

F

I

M

C

G

4

2

0.96

Y

1.80

G

T

H

I

I

M

C

G

4

3

0.88

Y

2.13

G

T

H

I

I

M

C

G

4

4

0.90

Y

0.84

G

T

H

F

F

M

C

G

3

5

0.91

Y

2.39

G

T

H

F

F

M

C

G

4

6

0.89

Y

1.83

G

T

H

I

I

M

C

G

4

7

0.84

Y

1.85

G

T

H

F

F

M

C

G

4

8

0.89

Y

2.73

G

T

H

I

I

M

C

G

4

9

0.93

Y

1.48

G

T

H

I

I

M

C

G

3

10

0.96

Y

2.05

G

T

H

I

I

M

C

G

4

11

0.78

Y

2.22

G

S

H

F

I

M

C

G

4

12

0.80

Y

2.35

G

T

H

F

I

M

C

G

4

13

0.89

Y

1.00

E

T

H

F

I

M

C

G

2

14

0.84

C

1.04

E

T

H

F

I

M

C

G

1

15

0.80

Y

2.71

G

T

H

F

F

M

C

G

4

16

0.82

Y

2.48

G

T

H

F

F

M

C

G

4

17

0.66

C

1.08

E

T

H

F

I

M

C

G

1

  1. Italic indicates either mutations or multiple copy number. A cut-off copy number of 1.5 and 1.6 are used to define pfmdr1and pfpm2 multiple copy number. Group 1 is for parasites containing WT-K13, WT-Exo, WT-PfCRT, and single copy number (CN) pfpm2. Group 2 is for parasites containing C580Y-K13, WT-Exo, WT-PfCRT, and single CN pfpm2. Group 3 is for parasites harboring C580Y-K13, E415G-Exo, Mut-PfCRT, and single CN pfpm2. Group 4 is for parasites having C580Y-K13, E415G-Exo, Mut-PfCRT, and multiple CN pfpm2
Back to article page

Malaria Journal

ISSN: 1475-2875

Contact us