Table 1 General characteristics of study subjects and exposure to potential drug–drug interactions
General characteristics | Patients: n (%) | Exposure to pDDIs [Patients: n (%)] |
|---|---|---|
Gender | ||
Male | 206 (51.8) | 77 (37.4) |
Female | 192 (48.2) | 71 (37) |
Age (years) | ||
≤ 20 | 96 (24.1) | 40 (41.7) |
21–40 | 176 (44.2) | 53 (30.1) |
> 40 | 126 (31.7) | 55 (43.7) |
Median (interquartile range) | 30 (22-50) | |
Drugs prescribed | ||
< 5 | 78 (19.6) | 5 (6.4) |
≥ 5 | 320 (80.4) | 143 (44.7) |
Median (interquartile range) | 7 (5–9) | |
Hospital stay (days) | ||
≤ 3 | 141 (35.4) | 32 (22.7) |
4–5 | 144 (36.2) | 56 (38.9) |
> 5 | 113 (28.4) | 60 (53.1) |
Median (interquartile range) | 4 (3–6) | |
Number of comorbidities | ||
No comorbidities | 179 (45) | – |
1–2 | 187 (46.9) | – |
≥ 3 | 32 (8) | – |
Comorbidities | ||
Hypertension | 52 (13.1) | 20 (38.5) |
Diabetes mellitus | 45 (11.3) | 27 (60) |
Urinary tract infection | 34 (8.5) | 13 (38.2) |
Hepatitis | 23 (5.8) | 11 (47.8) |
Ischemic heart disease | 15 (3.8) | 9 (60) |
Anaemia | 13 (3.3) | 3 (23.1) |
Dengue fever | 12 (3) | 5 (41.7) |
Meningitis | 11 (2.8) | 5 (41.7) |
Respiratory tract infection | 9 (2.3) | 2 (22.2) |
Thrombocytopenia | 9 (2.3) | 2 (22.2) |
Typhoid | 9 (2.3) | – |
Bicytopenia | 7 (1.8) | – |
Acute gastroenteritis | 6 (1.5) | – |
Asthma | 6 (1.5) | – |
Tuberculosis | 6 (1.5) | – |
Acute kidney injury | 5 (1.3) | – |
Pancytopenia | 5 (1.3) | – |
Decompensated chronic liver disease | 4 (1) | – |
Pneumonia | 4 (1) | – |
Congestive cardiac failure | 3 (0.8) each | – |
Miscellaneous | 72 (18)a | – |