Fig. 2

Bootstrap analysis of average annual economic cost per capita: unit cost (USD, 2014) and relative contribution of inputs by category. Colour segments of the stacked bars above correspond to the relative joint contribution of model inputs grouped into either of the five categories, describing intervention (green), setting (blue), scale (orange), price level (brown), and methods (red) to intervention unit cost. Proportions represent the joint contribution of model inputs within each category as a fraction of total variation in average annual economic cost per capita explained by the model. These were obtained by regressing cost per capita on model inputs sampled from 500 model parameter sets simultaneously drawn 10,000 times from a uniform distribution within the corresponding parameter range (Additional file 3). Model inputs by category are listed in Additional file 1: Table S2. Equivalent distributions for cost per outputs are shown in Additional file 1: Figure S1. RR Rapid Reporting, RACD reactive case detection, MDA Mass Drug Administration, IRS indoor residual spraying