Skip to main content

Table 1 Summary of animals subjected to 14-day toxicity study of FNDR-20123

From: Discovery of FNDR-20123, a histone deacetylase inhibitor for the treatment of Plasmodium falciparum malaria

Group no.

Dose of parent

Frequency of administration

Concentration (mg/mL)

Dose volume (mL/kg)

No. of animals sex/group

(mg/kg bw)

G1-Vehicle control

0.0

qda

0.0

10

5

G2-Low dose

50.0

qd

5.0

10

5

G3-Mid dose

100.0

qd

10.0

10

5

G4-High dose

150.0

qd

15.0

10

5

G5-TK

100.0

qd

10.0

10

3

  1. aqd–Once a day