Skip to main content

Table 1 Summary of animals subjected to 14-day toxicity study of FNDR-20123

From: Discovery of FNDR-20123, a histone deacetylase inhibitor for the treatment of Plasmodium falciparum malaria

Group no. Dose of parent Frequency of administration Concentration (mg/mL) Dose volume (mL/kg) No. of animals sex/group
(mg/kg bw)
G1-Vehicle control 0.0 qda 0.0 10 5
G2-Low dose 50.0 qd 5.0 10 5
G3-Mid dose 100.0 qd 10.0 10 5
G4-High dose 150.0 qd 15.0 10 5
G5-TK 100.0 qd 10.0 10 3
  1. aqd–Once a day