Table 7 Pharmacokinetic parameters of FNDR-20123
| Â | Infected | Normal | Normal | Normal |
|---|---|---|---|---|
Animal, strain | SCID mice | Balb/C mice | Balb/C mice | Balb/C mice |
Route of administration | Oral | Oral | Subcutaneous | Intramuscular |
Dose (mg/Kg) | 50 | 50 | 50 | 50 |
Tmax (h) | 1.00 | 1.00 | 0.08 | 0.08 |
Cmax (ng/mL) | 460 | 184 | 14039 | 15654 |
AUClast (h*ng/mL) | 1340 | 327 | 10,981 | 7224 |
t1/2 (h) | Not calculated | 2.02 | 9.21 | 8.72 |