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Table 8 Summary of body weights (g) in females and males (FNDR-20123)

From: Discovery of FNDR-20123, a histone deacetylase inhibitor for the treatment of Plasmodium falciparum malaria

Groups

Dose (mg/kg bw)

Female

Male

Day

1

7

14

1

7

14

G1

0

143.05

152.03

160.27

171.51

193.40

211.52

11.43

23.65

22.62

14.25

15.86

21.33

G2

50

146.45

150.70

161.49

166.04

190.40

209.30

6.69

4.32

4.76

11.77

7.67

10.54

G3

100

146.70

145.63

158.43

166.39

173.72

177.16

13.79

15.68

14.58

16.21

26.92

41.74

G4

150

144.18

139.82

142.91

170.86

180.10

188.27

10.00

14.44

20.97

10.31

11.32

12.22

  1. G5-toxicokinetic group
  2. Values are expressed as Mean ± SD