Discovery of FNDR-20123, a histone deacetylase inhibitor for the treatment of Plasmodium falciparum malaria

Malaria Journal

Table 9 Summary of Relative Organ Weights (g)–Males

Groups, sex and dose (mg/kg)	Fasting body weight (g) Mean ± SD	Brain	Heart	Liver	Kidney	Thymus	Spleen	Lungs	Testis	Epididymis
G1 M 0	191.68	0.92	0.35	4.02	0.91	0.13	0.48	0.96	1.45	0.30
G1 M 0	19.15	0.10	0.03	0.34	0.13	0.06	0.10	0.67	0.13	0.05
G2 M 50	189.75	0.91	0.36	4.13	0.88	0.09	0.38	0.69	1.44	0.26
G2 M 50	8.99	0.06	0.00	0.56	0.10	0.04	0.14	0.07	0.10	0.05
G3 M 100	163.82	1.25	0.46	5.62	1.12	0.10	0.80	0.99	1.94	0.28
G3 M 100	38.21	0.15	0.14	2.73	0.44	0.04	0.87	0.37	0.59	0.11
G4 M 150	174.95	0.98	0.35	3.72	0.91	0.10	0.21	0.76	1.54	0.34
G4 M 150	11.67	0.11	0.04	0.39	0.08	0.02	0.07	0.15	0.16	0.07

ISSN: 1475-2875