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Table 3 RDT Pf band positivity against pfhrp2-deleted and wild type panels according to RDT group

From: Impact of Plasmodium falciparum gene deletions on malaria rapid diagnostic test performance

RDT Group

Median positivitya (%) (min–max)

Pfhrp2-deleted panel

Wild type panel

(n = 400b)

Double-deleted

(n = 72b)

Single-deleted

(n = 88b)

1 (Pf-LDH) (n = 9)

63.9 (13.9–86.1)

59.1 (11.4–84.1)

93.8 (30.5–99.0)

2 (pan-LDH only) (n = 2)

95.1 (94.4–95.8)

96.0 (94.3–97.7)

99.5 (99.5–99.5)

3 (HRP2-only) (n = 4)

6.3 (0.0–15.3)

69.9 (61.4–92.0)

96.0 (91.5–98.0)

4 (HRP2-combination) (n = 17)

0.0 (0.0–20.8)

35.2 (1.1–80.7)

92.5 (70.3–98.2)

  1. For Group 2 (pan-LDH only) RDTs the pan band is used to determine positivity
  2. aPositivity was calculated for each RDT against the relevant parasite panel; median, minimum and maximum positivity were then calculated across the RDTs within each group, respectively. Only valid RDT results are included in positivity calculations
  3. bEach sample in each panel was tested against four RDTs of the same product