From: Impact of Plasmodium falciparum gene deletions on malaria rapid diagnostic test performance
RDT Group | Median positivitya (%) (min–max) | ||
---|---|---|---|
Pfhrp2-deleted panel | Wild type panel (n = 400b) | ||
Double-deleted (n = 72b) | Single-deleted (n = 88b) | ||
1 (Pf-LDH) (n = 9) | 63.9 (13.9–86.1) | 59.1 (11.4–84.1) | 93.8 (30.5–99.0) |
2 (pan-LDH only) (n = 2) | 95.1 (94.4–95.8) | 96.0 (94.3–97.7) | 99.5 (99.5–99.5) |
3 (HRP2-only) (n = 4) | 6.3 (0.0–15.3) | 69.9 (61.4–92.0) | 96.0 (91.5–98.0) |
4 (HRP2-combination) (n = 17) | 0.0 (0.0–20.8) | 35.2 (1.1–80.7) | 92.5 (70.3–98.2) |