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Table 4 Non-falciparum false positivity rates for combination RDTs in Groups 1 (Pf-LDH) and 4 (HRP2-combination)

From: Impact of Plasmodium falciparum gene deletions on malaria rapid diagnostic test performance

RDT Groupa

Median non-falciparum false positivity rateb (%) (min–max)

Double-deleted samples

(n = 72)

Single-deleted samples

(n = 88)

Wild type samples

(n = 400)

1 (Pf-LDH) (n = 3)

13.9 (0-55.6)

21.6 (0-34.1)

2.0 (0-10.3)

4 (HRP2-combination) (n = 17)

1.4 (0-81.9)

1.1 (0-43.2)

0.8 (0 – 3.0)

  1. aRDT Groups 2 (pan-LDH only) and 3 (HRP2-only) are not included as it was not possible to determine non-falciparum false positivity rates because these RDTs do not differentiate species or have the capacity to detect non-falciparum infections, respectively
  2. bNon-falciparum false positivity rate was calculated for each RDT against the relevant parasite panel; median, minimum and maximum values were then calculated across the RDTs within each group. Only valid RDT results are included in non-falciparum false positivity rate calculations
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Malaria Journal

ISSN: 1475-2875

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