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Table 3 Prevalence of pfmdr1 N86Y alleles among the study population

From: Prevalence and factors associated with carriage of Pfmdr1 polymorphisms among pregnant women receiving intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-SP) and artemether-lumefantrine for malaria treatment in Burkina Faso

Codon

N86 allele

86Y allele

N86 + 86Y alleles

Total 86Y allele carriage

P*

n

% (95%CI)

n

% (95%CI)

n

% (95%CI)

n

% (95%CI)

Total study population

 ANC-1 (N = 151)

131

86.8 (80.3–91.7)

5

3.3 (1.1–7.6)

15

9.9 (5.7–15.9)

20

13.2 (8.3–19.7)

0.77

 Delivery (N = 116)

102

87.9 (80.6–93.2)

2

1.7 (0.2–6.1)

12

10.3 (5.5–17.4)

14

12.1 (6.8–19.4)

 

Women infected at ANC-1 and at delivery

 ANC-1 (N = 38)

35

92.1 (78.6–98.3)

1

2.6 (0.1–13.8)

2

5.3 (0.6–17.8)

3

7.9 (1.7–21.4)

0.25

 Delivery (N = 31)

26

83.9 (66.3–94.5)

0

0

5

16.1 (5.4–33.7)

5

16.1 (5.4–33.7)

 

Women who received standard IPTp-SP

 ANC-1 (N = 81)

73

90.1 (81.5–95.6)

1

1.2 (0.03–6.7)

7

8.7 (3.6–17.0)

8

9.9 (4.4–18.5)

0.63

 Delivery (N = 56)

49

87.5 (75.9–94.8)

2

3.6 (0.4–12.3)

5

8.9 (3.0–19.6)

7

12.5 (5.2–24.1)

 

Women who received CSST/IPTp-SP

 ANC-1 (N = 70)

58

82.9 (72.0–90.8)

4

5.7 (1.6–14.0)

8

11.4 (5.1–21.3)

12

17.1 (9.2–28.0)

0.38

 Delivery (N = 60)

53

88.3 (77.4–95.2)

0

0

7

11.7 (4.8–22.6)

7

11.7 (4.8–22.6)

 
  1. *P value for total mutant (86Y) allele carriage versus wild-type (N86) allele carriage