|
Codon
|
N86 allele
|
86Y allele
|
N86 + 86Y alleles
|
Total 86Y allele carriage
|
P*
|
|---|
|
n
|
% (95%CI)
|
n
|
% (95%CI)
|
n
|
% (95%CI)
|
n
|
% (95%CI)
|
|---|
|
Total study population
|
|
ANC-1 (N = 151)
|
131
|
86.8 (80.3–91.7)
|
5
|
3.3 (1.1–7.6)
|
15
|
9.9 (5.7–15.9)
|
20
|
13.2 (8.3–19.7)
|
0.77
|
|
Delivery (N = 116)
|
102
|
87.9 (80.6–93.2)
|
2
|
1.7 (0.2–6.1)
|
12
|
10.3 (5.5–17.4)
|
14
|
12.1 (6.8–19.4)
| |
|
Women infected at ANC-1 and at delivery
|
|
ANC-1 (N = 38)
|
35
|
92.1 (78.6–98.3)
|
1
|
2.6 (0.1–13.8)
|
2
|
5.3 (0.6–17.8)
|
3
|
7.9 (1.7–21.4)
|
0.25
|
|
Delivery (N = 31)
|
26
|
83.9 (66.3–94.5)
|
0
|
0
|
5
|
16.1 (5.4–33.7)
|
5
|
16.1 (5.4–33.7)
| |
|
Women who received standard IPTp-SP
|
|
ANC-1 (N = 81)
|
73
|
90.1 (81.5–95.6)
|
1
|
1.2 (0.03–6.7)
|
7
|
8.7 (3.6–17.0)
|
8
|
9.9 (4.4–18.5)
|
0.63
|
|
Delivery (N = 56)
|
49
|
87.5 (75.9–94.8)
|
2
|
3.6 (0.4–12.3)
|
5
|
8.9 (3.0–19.6)
|
7
|
12.5 (5.2–24.1)
| |
|
Women who received CSST/IPTp-SP
|
|
ANC-1 (N = 70)
|
58
|
82.9 (72.0–90.8)
|
4
|
5.7 (1.6–14.0)
|
8
|
11.4 (5.1–21.3)
|
12
|
17.1 (9.2–28.0)
|
0.38
|
|
Delivery (N = 60)
|
53
|
88.3 (77.4–95.2)
|
0
|
0
|
7
|
11.7 (4.8–22.6)
|
7
|
11.7 (4.8–22.6)
| |
- *P value for total mutant (86Y) allele carriage versus wild-type (N86) allele carriage
