Table 1 Observed the overall frequency of mutations in Pfdhfr and Pfdhps
Gene | Mutations | Wild type (%) | Mutation (%) | Mixed type (%) | Total |
|---|---|---|---|---|---|
Pfdhfr | N51I | 22 (7.3) | 272 (90.7) | 6 (2.0) | 300 |
C59R | 37 (12.3) | 254 (84.7) | 9 (3.0) | 300 | |
S108N | 9 (3.0) | 284 (94.7) | 7 (2.3) | 300 | |
I164L | 299 (99.7) | 1 (0.3) | 0 (0.0) | 300 | |
Pfdhps | S436A | 191 (65.9) | 79 (27.2) | 20 (6.9) | 290 |
A437G | 38 (13.1) | 229 (79.0) | 23 (7.9) | 290 | |
K540E | 204 (70.3) | 63 (21.7) | 23 (7.9) | 290 | |
A581G | 248 (85.5) | 26 (9.0) | 16 (5.5) | 290 | |
A613S | 258 (89.0) | 31 (11.0) | 1 (0.3) | 290 |