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Table 5 Presence of HRP2, pLDH-Pan, and pLDH-Pf antigen by type of result from RT-qPCR, cRDT and uRDT in 233 samples

From: Field performance of ultrasensitive and conventional malaria rapid diagnostic tests in southern Mozambique

 

HRP2 positive

pLDH-Pan positive

pLDH-Pf positive

N = 160/223

N = 114/223

N = 97/223

n (%)

n (%)

n (%)

RT-qPCR positive

N = 134/223

cRDT positive = TP

N = 71

71 (100.0)

56 (78.9)

56 (78.9)

cRDT negative = FN

N = 63

46 (73.0)

38 (60.3)

33 (52.4)

uRDT positive = TP

N = 80

79 (98.8)

61 (76.3)

59 (73.8)

uRDT negative = FN

N = 54

38 (70.4)

33 (61.1)

30 (55.6)

RT-qPCR negative

N = 89/223

cRDT positive = FP

N = 32

27 (84.4)

11 (34.4)

8 (25.0)

cRDT negative = TN

N = 57

16 (28.1)

9 (15.8)

0 (0)

uRDT positive = FP

N = 41

33 (80.5)

12 (29.3)

8 (19.5)

uRDT negative = TN

N = 48

10 (20.8)

8 (16.7)

0 (0)

  1. TP True positive, FP false positive, TN true negative, FN false negative, HRP2 histidine-rich protein 2, pLDH Plasmodium lactate dehydrogenase, pLDH-Pan pan specific pLDH, pLDH-Pf P. falciparum specific pLDH
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Malaria Journal

ISSN: 1475-2875

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