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Table 5 Inhibitory concentrations of the affinity maturated antibodies against the P. falciparum strains 3D7, HB3, K1 and W2mef

From: Isolation and light chain shuffling of a Plasmodium falciparum AMA1-specific human monoclonal antibody with growth inhibitory activity

P. falciparum strain EC50 (95%CI) (mg/mL)
Antibody
OcheA-9 OcheA-16 OcheA-17 OcheA-17B
3D7 1.19 > 2 0.55 0.29
(0.79–1.79)   (0.43–0.70) (0.24–0.34)
HB3 1.07 1.18 0.45 0.23
(0.61–1.86) (0.65–2.13) (0.25–0.81) (0.17–0.32)
K1 0.77 1.50 0.37 0.31
(0.49–1.21) (0.79–2.87) (0.24–0.55) (0.26–0.38)
W2mef 0.55 > 2 0.30 > 2
(0.31–0.96)   (0.26–0.34)