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Table 3 Sensitivity, specificity, positive and negative predictive values of microscopy, Pf RDT and HSPf RDT compared to PCR as gold standard

From: Performance evaluation of the highly sensitive histidine‐rich protein 2 rapid test for Plasmodium falciparum malaria in North-West Tanzania

  PCR Positive (n = 171) PCR negative (n = 225) Sensitivity % (CI95) Specificity %(CI95) PPV% (CI95) NPV% (CI95)
Microscopy
 Positive (n = 87) 70 17 40.0 (32.6–47.7) 92.4 (88.0–95.5) 80.5 (70.6–88.2) 66.1 (60.6–71.4)
 Negative (n = 310) 105 205
Pf RDT
 Positive (n = 110) 99 11 56.5 (48.8–64.0) 95.0 (91.3–97.5) 90.0
(82.8–94.9)
73.5 (68.0–78.5)
 Negative (n = 287) 76 211
HSPf RDT
 Positive (n = 132) 117 15 69.9 (59.3–73.8) 93.2 (89.1–96.2) 88.6 (82–93.5) 78.1 (72.6–82.9)
 Negative (n = 265) 58 207
  1. PPV positive predictive value, NPV negative predictive value, CI95 95% confidence interval
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