Table 4 Sensitivity, specificity and predictive values of microscopy, routine Pf RDT and HSPf RDT compared to PCR as gold standard by age group
Age | Sensitivity % (95CI) | Specificity % (95CI) | PPV % (95CI) | NPV % (95CI) |
|---|---|---|---|---|
Microscopy | ||||
5–10 | 52.5 (38.3–71.4) | 93.7 (79.2–99.2) | 91.3 (72.0–98.9) | 61.2 (46.2–74.8) |
11–15 | 58.3 (46.8–81.4) | 100 (80.5–100) | 100 (83.9–100) | 51.6 (33.1–69.8) |
> 15 | 28.2 (20.3–39.8) | 91.4 (85.0–94.5) | 65.1 (49.1–79.0) | 69.1 (62.7–75.0) |
P-value* | 0.070 | 0.001 | 0.98 | 0.886 |
Pf | ||||
5–10 | 75 (58.8–87.3) | 93.8 (79.2–99.2) | 93.8 (79.2–99.2) | 75 (58.8–87.3) |
11–15 | 77.8 (65.5–93.2) | 75.0 (52.4–93.6) | 87.5 (71.0–96.5) | 60 (36.0–80.9) |
> 15 | 41.4 (32.3–52.7) | 97.1 (93.5–99.1) | 89.1 (76.4–96.4) | 75.2 (69.1–80.7) |
P-value* | 0.051 | 0.835 | 0.980 | 0.980 |
HSPf | ||||
5–10 | 80.0 (64.4–90.9) | 93.8 (79.2–99.2) | 94.1 (80.3–99.3) | 78.9 (62.7–90.4) |
11–15 | 86.1 (76.3–98.1) | 62.5 (41.0–86.7) | 83.8 (68.0–93.8) | 67 (38.4–88.2) |
> 15 | 54.5 (45.2–65.8) | 96.0 (91.9–98.4) | 88.5 (77.8–95.3) | 78.7 (72.6–84.1) |
P-value* | 0.196 | 0.640 | 0.945 | 0.999 |