Table 1 Details of the Plasmodium spp. proteins expressed in this study
From: A panel of recombinant proteins from human-infective Plasmodium species for serological surveillance
Sp. | Official nomenclature | Synonym/s | Accession number | Region expressed | Length (aa) | Exp. level | PlasmoDB, previous ID | Addgene ID |
|---|---|---|---|---|---|---|---|---|
P. falciparum | MSP1* | MSA1, Pf190, Pf195 | PF3D7_0930300 | V20-S1701 | 1682 | Low | Merozoite surface protein 1 | 47709 |
AMA1* | Pf83, RMA1, PfAMA1 | PF3D7_1133400 | Q25-T541 | 517 | High | Apical membrane antigen 1, PF11_0344 | 47741 | |
P92* | Pf92 | PF3D7_1364100 | A26-S770 | 745 | Low | 6-cysteine protein, PF13_0338 | 47728 | |
MSP4 | PF3D7_0207000 | Y29-S253 | 225 | Low | Merozoite surface protein 4, PFB0310C | 47717 | ||
MSP5 | PF3D7_0206900.1 | N22-S251 | 230 | Low | Merozoite surface protein 5, PFB0305C | 47718 | ||
P12* | Pf12, Pfs12 | PF3D7_0612700 | H26-S323 | 298 | High | 6-cysteine protein, MAL6P1, PFF0615C | 47725 | |
GAMA | PSOP9 | PF3D7_0828800 | L22-P710 | 689 | Med | GPI-anchored micronemal antigen | 47747 | |
MSP10* | PF3D7_0620400 | H27-S503 | 477 | Med | Merozoite surface protein 10, MAL6P1.221, PFF0995C | 47719 | ||
P38 | Pf38, Pfs38 | PF3D7_0508000 | Q22-S328 | 307 | High | 6-cysteine protein, PFE0395C | 47727 | |
MSP3.1* | MSP3, SPAM | PF3D7_1035400 | K26-H354 | 328 | Med | Merozoite surface protein 3, PF10_0345 | 47731 | |
P41 | Pf41, Pfs41 | PF3D7_0404900 | K21-S378 | 358 | High | 6-cysteine protein, PFD0240C | 47739 | |
MSP7 | PF3D7_1335100 | T28-M351 | 324 | Med | Merozoite surface protein 7, PF13_0197 | 47735 | ||
HPzz* | PFA0210c | PF3D7_0104200 | Y24-D466 | 443 | Low | StAR-related lipid transfer protein, MAL1P1.33 | 50821 | |
P. vivax | MSP4 | PVX_003775 | A26-S227 | 202 | Low | Merozoite surface protein 4, putative, PV003775 | 68510 | |
MSP5* | PVX_003770 | R22-S367 | 346 | Med | Merozoite surface protein 5, PV003770 | 68511 | ||
P12* | PVX_113775 | F24-A339 | 316 | Med | 6-cysteine protein, PV113775 | 68516 | ||
GAMA | PVX_088910 | L21-S749 | 729 | Med | GPI-anchored micronemal antigen, putative, PV088910 | 68522 | ||
CyRPA | PVX_090240 | T23-D366 | 344 | Med | Cysteine-rich protective antigen, putative, PV090240 | 68525 | ||
HPzz* | PVX_081550 | R23-F495 | 473 | Low | StAR-related lipid transfer protein, putative, PV081550 | 68532 | ||
P38* | PVX_097960 | K29-G334 | 306 | Med | 6-cysteine protein, PV097960 | 68518 | ||
MSP7.1* | PVX_082700 | E22-Y420 | 399 | Med | Merozoite surface protein 7 (MSP7), PV082700 | 68512 | ||
MSP3γ | MSP3.1 | PVX_097670 | N21-K845 | 825 | Med | Merozoite surface protein 3, PV097670 | 68506 | |
P41* | PVX_000995 | E22-E384 | 363 | Med | 6-cysteine protein, PV000995 | 68519 | ||
P. malariae | CyRPA | PmUG01_05040800 | E20-D358 | 339 | Low | Cysteine-rich protective antigen, putative | 126817 | |
GAMA | PmUG01_05017200 | L22-S764 | 743 | High | GPI-anchored micronemal antigen | 126818 | ||
MSP10* | PmUG01_11043200 | N27-S389 | 363 | Low | Merozoite surface protein 10, putative | 126819 | ||
MSP4 | PmUG01_04025600 | Y29-S206 | 178 | Low | Merozoite surface protein 4, putative | 126820 | ||
MSP5* | PmUG01_04025700 | K22-L291 | 270 | High | Merozoite surface protein 5 | 126821 | ||
P12 | P12p | PmUG01_11050400 | Y19-S333 | 315 | Low | 6-cysteine protein | 126822 | |
P38 | PmUG01_06016900 | M1-A310 | 310 | Low | 6-cysteine protein, putative | 126823 | ||
P41* | PmUG01_03015000 | Q23-D374 | 352 | Med | 6-cysteine protein, putative | 126824 | ||
MSP3.10 | PmUG01_06022000 | K24-I525 | 522 | High | Merozoite surface protein 3, putative | 126825 | ||
MSP3.5 | PmUG01_06022600 | N21-S562 | 542 | High | Merozoite surface protein 3, putative | 126826 | ||
MSP7.1 | PmUG01_12029500 | R25-I442 | 418 | High | MSP7-like protein, putative | 126827 | ||
MSP7.4 | PmUG01_12029900 | K22-V394 | 373 | High | MSP7-like protein, putative | 126828 | ||
P. ovale | CyRPA | POVCU1_054880 | S20-D359 | 340 | Med | Cysteine-rich protective antigen, putative, SBS99762.1 | 126829 | |
GAMA | PocGH01_05012100 | L22-S755 | 734 | High | GPI-anchored micronemal antigen, putative | 126830 | ||
MSP10* | PocGH01_11036900 | Y27-S430 | 404 | High | Merozoite surface protein 10, putative | 126831 | ||
MSP4 | PocGH01_04023000 | N26-S209 | 184 | High | Merozoite surface protein 4, putative | 126832 | ||
MSP5 | PocGH01_04023100 | F20-S311 | 292 | High | Merozoite surface protein 5, putative | 126833 | ||
P12 | P12p | PocGH01_11044100 | E23-S301 | 279 | Low | 6-cysteine protein | 126834 | |
P38 | PocGH01_10033500 | K25-S332 | 308 | Low | 6-cysteine protein, putative | 126835 | ||
P41* | PocGH01_03012400 | E16-E375 | 360 | Med | 6-cysteine protein, putative | 126836 | ||
MSP3.5* | PocGH01_10038700 | K24-P480 | 457 | Med | Merozoite surface protein 3, putative | 126837 | ||
MSP3.6 | PocGH01_10038800 | K24-S732 | 709 | Low | Merozoite surface protein 3, putative | 126838 | ||
MSP7.12 | PocGH01_12028800 | K23-T441 | 419 | Med | MSP7-like protein, putative | 126839 | ||
MSP7.8 | PocGH01_12028400 | K23-T379 | 357 | Med | MSP7-like protein, putative | 126840 | ||
P. knowlesi | CyRPA | PKNH_0515800 | N23-E366 | 344 | Med | Cysteine-rich protective antigen, putative, PKH_052740 | 126841 | |
GAMA | PSOP9 | PKNH_1322900 | L21-S700 | 680 | Med | GPI-anchored micronemal antigen, putative, PKH_050210 | 126842 | |
MSP10* | PKNH_1129800 | N27-S417 | 391 | High | Merozoite surface protein 10, putative, PKH_112880 | 126940 | ||
MSP4 | PKNH_0414100 | D26-S182 | 157 | Med | Merozoite surface protein 4, putative, PKH_041300 | 126843 | ||
MSP5 | PKNH_0414200 | H22-S354 | 333 | Med | Merozoite surface protein 5, PKH_041310 | 126844 | ||
P12* | PKNH_1137300 | F24-S323 | 300 | Med | 6-cysteine protein, PKH_113620 | 126845 | ||
P38* | PKNH_1025600 | K3-S367 | 365 | Low | 6-cysteine protein, PKH_102490 | 126846 | ||
P41 | PKNH_0303000 | E22-E393 | 372 | High | 6-cysteine protein, PKH_030970 | 126847 | ||
P92 | PKNH_1107200 | D24-P857 | 834 | Med | 6-cysteine protein, PKH_110660 | 126848 |