Fig. 6

Malnourished mice express high Tbet, but reduced activated effector CD4⁺ T cells. Adults C57Bl/6 mice were moderately malnourished through food limitation by only allowing mice access to food for 4 h daily for 3 weeks, while controls had unlimited access to food. All mice were infected with a 1 × 10⁵ dose of P. chabaudi AS and sacrificed at day 9 post-infection. Summary graphs shows mouse weight in grams over a weeks post diets, b days post-infection. Numbers of c activated effector CD4⁺ T cells d IFNγ and e TNF producing CD4⁺ T cells. e, f Percent and number of Tbet expressing CD4⁺ T cells. Data represents an average of 5 mice per group and error bars represent SEM. Significance was determined by two-tailed t test with 95% confidence, *p < 0.05. Mal malnourished, Uninf uninfected control mice