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Fig. 9 | Malaria Journal

Fig. 9

From: Moringa oleifera treatment increases Tbet expression in CD4+ T cells and remediates immune defects of malnutrition in Plasmodium chabaudi-infected mice

Fig. 9

Nutritional supplementation with Moringa slightly increase percent of IL-2 and IL-10. Adult C57Bl/6 mice were malnourished by food limitation by allowing mice access to food for 4 h daily for 4 weeks prior to infection. A second group of malnourished mice were supplemented with Moringa (500 mg per mouse), while controls had constant supply of food. All mice were infected with a 1 × 105 dose of P. chabaudi AS and sacrificed at day 9 post-infection. Summary graphs show a Percent and b Number of IL-2 producing CD4+ T cells. c Percent and d numbers of IL-10 producing CD4+ T cells determined using intracellular cytokine staining. Data represents an average of 5 mice per group and error bars represent SEM. Significance was determined by two-tailed t test with 95% confidence. n.s no significance difference Mal malnourished, Mal & MO malnourished supplemented with Moringa

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