Table 2 Estimates of DNA sequence polymorphism and tests of neutrality of PvLDH and PfLDH in the global P. vivax and P. falciparum isolates
Segregating sites (S) | Singleton variable sites | K | H | Hd ± SD | π ± SD | dN–dS ± SD | Tajima’s D (P value) | Fu and Li’s D (P value) | Fu and Li’s F (P value) | |
|---|---|---|---|---|---|---|---|---|---|---|
PvLDH (n = 100) | 59 | 53 | 1.804 | 35 | 0.776 ± 0.032 | 0.0021 ± 0.0003 | 0 | − 2.714 (P < 0.001) | − 8.118 (P < 0.02) | − 7.073 (P < 0.02) |
PfLDH (n = 334) | 31 | 29 | 0.374 | 22 | 0.297 ± 0.031 | 0.0005 ± 0.0001 | − 0.004 ± 0.002 | − 2.505 (P < 0.001) | − 10.126 (P < 0.02) | − 8.285 (P < 0.02) |