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Table 2 Estimates of DNA sequence polymorphism and tests of neutrality of PvLDH and PfLDH in the global P. vivax and P. falciparum isolates

From: Genetic diversity of Plasmodium vivax and Plasmodium falciparum lactate dehydrogenases in Myanmar isolates

 Segregating sites (S)Singleton variable sitesKHHd ± SDπ ± SDdN–dS ± SDTajima’s D (P value)Fu and Li’s D (P value)Fu and Li’s F (P value)
PvLDH (n = 100)59531.804350.776 ± 0.0320.0021 ± 0.00030− 2.714 (P < 0.001)− 8.118 (P < 0.02)− 7.073 (P < 0.02)
PfLDH (n = 334)31290.374220.297 ± 0.0310.0005 ± 0.0001− 0.004 ± 0.002− 2.505 (P < 0.001)− 10.126 (P < 0.02)− 8.285 (P < 0.02)
  1. S, Number of segregating sites; K, average number of nucleotide differences; H, number of haplotypes; Hd, haplotype diversity; π, observed average pairwise nucleotide diversity; dN, rate of non-synonymous mutations; dS, rate of synonymous mutations