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Table 2 Estimates of DNA sequence polymorphism and tests of neutrality of PvLDH and PfLDH in the global P. vivax and P. falciparum isolates

From: Genetic diversity of Plasmodium vivax and Plasmodium falciparum lactate dehydrogenases in Myanmar isolates

  Segregating sites (S) Singleton variable sites K H Hd ± SD π ± SD dN–dS ± SD Tajima’s D (P value) Fu and Li’s D (P value) Fu and Li’s F (P value)
PvLDH (n = 100) 59 53 1.804 35 0.776 ± 0.032 0.0021 ± 0.0003 0 − 2.714 (P < 0.001) − 8.118 (P < 0.02) − 7.073 (P < 0.02)
PfLDH (n = 334) 31 29 0.374 22 0.297 ± 0.031 0.0005 ± 0.0001 − 0.004 ± 0.002 − 2.505 (P < 0.001) − 10.126 (P < 0.02) − 8.285 (P < 0.02)
  1. S, Number of segregating sites; K, average number of nucleotide differences; H, number of haplotypes; Hd, haplotype diversity; π, observed average pairwise nucleotide diversity; dN, rate of non-synonymous mutations; dS, rate of synonymous mutations