Fig. 2

Diversity and differentiation of P. falciparum in mainland Tanzania and Zanzibar. a Average pairwise sequence diversity (theta_pi) per base pair in different compartments of the core genome: all sites, fourfold degenerate (“synonymous”) sites, zerofold degenerate (“non-synonymous”) sites, and coding regions of putative drug-resistance genes. Points are coloured by population; error bars give 95% bootstrap CIs. b Tajima’s D in same classes of sites as in a. c Distribution of F_st between mainland Tanzania and Zanzibar isolates, calculated in 5 kb windows. Vertical lines mark 25th, 50th and 75th percentiles