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Table 3 Plasma protein binding (%) of naphthoquine (NQ) in male and female mice, rats, and humans

From: The gender-related variability in the pharmacokinetics and antiplasmodial activity of naphthoquine in rodents

Species

0.1 (μg/mL)

1.0 (μg/mL)

Mice (male)

82.55% ± 0.30%

82.55% ± 0.31%

Mice (female)

82.27% ± 0.30%

82.34% ± 0.41%

Rat (male)

82.57% ± 0.29%

82.44% ± 0.35%

Rat (female)

82.54% ± 0.24%

82.41% ± 0.30%

Human (male)

82.47% ± 0.32%

82.52% ± 0.31%

Human (female)

82.42% ± 0.22%

82.48% ± 0.24%