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Table 3 Plasma protein binding (%) of naphthoquine (NQ) in male and female mice, rats, and humans

From: The gender-related variability in the pharmacokinetics and antiplasmodial activity of naphthoquine in rodents

Species0.1 (μg/mL)1.0 (μg/mL)
Mice (male)82.55% ± 0.30%82.55% ± 0.31%
Mice (female)82.27% ± 0.30%82.34% ± 0.41%
Rat (male)82.57% ± 0.29%82.44% ± 0.35%
Rat (female)82.54% ± 0.24%82.41% ± 0.30%
Human (male)82.47% ± 0.32%82.52% ± 0.31%
Human (female)82.42% ± 0.22%82.48% ± 0.24%