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Table 2 Distribution of pfk13 and pfcrt-K76T mutations

From: Assessment of Plasmodium falciparum anti-malarial drug resistance markers in pfk13-propeller, pfcrt and pfmdr1 genes in isolates from treatment failure patients in Democratic Republic of Congo, 2018–2019

Site Positive PfPCR
N (%)
Pfcrt gene pfK13 gene
Pf successfully sequenced
N
K76T
N
K76T
%
(95% CI)
Pf successfully sequenced
N
Mutant Pf
N
Mutant Pf
%
(95% CI)
NS mutation
Bolenge 70 (79.5) 62 21 33.9 (22.3–47.0) 60 2 3.3 (0.4–11.5) F506L, N554K
Fungurume 63 (75.9) 60 6 10.0 (3.8–20.5) 58 1 1.7 (0.0–9.2) A557S
Kabondo 17 (85.0) 16 3 18.8 (4.0–45.6) 17 0 0.0 (0.0–16.2)
Katana 95 (66.4) 91 70 76.9 (66.9–85.1) 86 2 2.3 (0.3–8.1) N498I, D516E
Kingasani 92 (81.4) 81 27 33.3 (23.2–44.7) 80 2 2.5 (0.3–8.7) E507V, G538S
Vanga 27 (100.0) 25 12 48.0 (27.8–68.7) 24 0 0.0 (0.0–11.7)
Total 364 (76.8) 335 139 41.5 (36.2–47.0) 325 7 2.2 (0.9–4.4)  
  1. N number, PfPCR Plasmodium falciparum polymerase chain reaction, NS non-synonymous