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Fig. 4 | Malaria Journal

Fig. 4

From: Systematic identification of plausible pathways to potential harm via problem formulation for investigational releases of a population suppression gene drive to control the human malaria vector Anopheles gambiae in West Africa

Fig. 4

Pathway 2 Biodiversity: Potentially broader tolerances for humidity, temperature, salinity, or desiccation in dsxFCRISPRh transgenics could reduce densities of valued species or ecosystem services. Were the transgenic to show a broadening of tolerance for environmental conditions, this could result in increased competition with existing species in its current range, as well as new competition with new species in new range. Transgenics with broadened tolerance for humidity and temperature could, for example, be expected to show extended survival into dry season compared to non-transgenic. The net effect of a population suppression gene drive could ultimately reduce this specific harm by reducing the density of mosquitoes, including transgenic ones

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Malaria Journal

ISSN: 1475-2875

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