Fig. 4

Recurrence rates following the treatment of acute P. vivax malaria in trials with different anti-malarial drugs, but without 8-aminoquinolines, in which there was frequent assessment [8,9,10,11,12,13,14,15,16, 18,19,20,21,22, 24, 25, 28, 30, 35, 61, 67,68,69]. The percentages are the proportions of all recurrences observed by 120 days over time. They show more rapid reappearance (presumed relapse) of vivax malaria with more rapidly eliminated drugs. Left (a): Individual trials (light blue shows two trials from the Thailand–Myanmar border where there is low grade chloroquine resistance, darker blue lines are from trials conducted in areas where P. vivax is generally more chloroquine sensitive). Right (b): average profiles