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Table 2 Prevalence and density of P. vivax at baseline and endpoint

From: Gametocyte carriage of Plasmodium falciparum (pfs25) and Plasmodium vivax (pvs25) during mass screening and treatment in West Timor, Indonesia: a longitudinal prospective study

  Baseline Endpoint p value OR/GMR (95%CI)
Parasite prevalence
 By microscopy 43/811 (5%)a 35/740 (5%)b 0.643 0.89 (0.54–1.44)
 By PCR 183/811 (23%) 135/740 (18%) 0.038* 0.77 (0.59–0.99)*
 By either test 192/811 (24%) 142/740 (19%) 0.035* 0.77 (0.59–0.98)*
 Median parasitaemia/µL (IQR) (microscopy) 112 (48–1000) 80 (16–1080) 0.832  
 Median 18S copies/µL (IQR) (qPCR) (n baseline = 115, endpoint = 74) 192.2 (60.6–605.2) 177.7 (72.7–1535.0) 0.719  
Gametocyte prevalence
 By microscopy 9/811 (1.1%) 14/740 (1.9%) 0.215 1.72 (0.69–4.53)
 By pvs25 49/744 (7%) 39/704 (5%) 0.442 0.83 (0.52–1.31)
 By either test 49/744 (7%) 39/704 (5%) 0.442 0.83 (0.52–1.31)
Gametocyte density (per μL)
 By microscopy (median) (IQR) 160 (28–200) 64 (32–170) 0.516  
 By pvs25 (geometric mean) (95%CI) 56.4 (23.8–134.0) 65.6 (26.5–162.2) 0.810 0.9 (0.2–3.0)
  1. OR odds ratio, GMR geometric mean ratio
  2. aNine and bseven subjects were not confirmed by PCR during baseline and endpoint, respectively. This is presumably due to degraded DNA and possible LM false positive as 11 of 16 (69%) showed negative microscopy during cross check.
  3. *p < 0.05