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Table 4 Fever and parasite clearance reported in efficacy studies in Ethiopia (2004–2020)

From: Efficacy and safety of artemether–lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Ethiopia: a systematic review and meta-analysis

Study

Patient Enrolled (N)

Patient available

Patient Included

Fever clearance (%)

Parasite clearance (%)

Supervised

D1

D2

D3

D1

D2

D3

Abamecha et al. [35]

80

76

72

52.5

87.2

97.5

61.2

81.2

96.2

Partial

Teklemariam et al. [44]

92

79

78

80.0

97.8

100.0

33.0

84.4

100.0

Partial

Deressa et al. [42]

80

75

69

62.5

93.7

97.5

67.5

85.0

95.0

Partial

Nega et al. [39]

91

85

83

78.7

94.3

97.7

69.7

95.5

100.0

Partial

Wudneh et al. [49]

91

81

80

69.6

97.8

100.0

23.6

91.0

100.0

Partial

Kanche et al. [48]

88

86

86

N/R

59.1

93.2

N/R

72.2

94.3

Partial

Mekonnen et al. [38]

93

89

84

88.1

94.4

100.0

88.8

96.6

100.0

Partial

Ebstie et al. [47]

134

130

128

NR

NR

87.9

NR

85.9

96.1

Partial

Getnet et al. [40]

80

80

74

75.0

91.3

96.2

73.8

91.3

94.9

Partial

Mulu et al. [45]

66

60

58

89.4

98.5

100.0

84.8

93.9

100.0

NR

Eshetu et al. [36]

348

315

312

NR

96.7

99.1

NR

98.2

99.4

Non-supervised

Kinfu et al. [43]

73

71

69

NR

NR

100.0

NR

100.0

100.0

Partial

Hwang et al. [37]

119

112

111

65.2

90.5

93.0

NR

93.1

99.1

Partial

Assefa et al. [41]

90

82

79

NR

NR

100

98

NR

100.0

Partial

Kefyalew et al. [46]

102

102

102

44.1

82.4

93.1

NR

NR

NR

Partial