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Fig. 2 | Malaria Journal

Fig. 2

From: A randomized, double-blind, phase 2b study to investigate the efficacy, safety, tolerability and pharmacokinetics of a single-dose regimen of ferroquine with artefenomel in adults and children with uncomplicated Plasmodium falciparum malaria

Fig. 2

Study analysis sets. 1 Safety analyses were conducted in the overall Safety Set, including all randomized patients who received at least one dose or part of a dose of the study drug, regardless of age and region (n = 373). In addition, safety analyses were also performed in the 3 separate Safety Subsets including the African patients ≤ 5 years, the African patients > 5 years and the Asian patients, respectively. 2 The primary efficacy analysis was conducted in the PP Set at Day 28 (African patients ≤ 5 years only). Note: three African sites had quality issues related to the reading of the slides by microscopy. For one site, issues were detected before database lock and the patients were excluded from the PP Sets. All doses of artefenomel and ferroquine are expressed as adult-equivalent doses

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Malaria Journal

ISSN: 1475-2875

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