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Fig. 6 | Malaria Journal

Fig. 6

From: A randomized, double-blind, phase 2b study to investigate the efficacy, safety, tolerability and pharmacokinetics of a single-dose regimen of ferroquine with artefenomel in adults and children with uncomplicated Plasmodium falciparum malaria

Fig. 6

Relationship between parasite clearance half-life and kelch-13 genotype by region (PP Sets). Only patients with both genotyping and PCt1/2 results were included (n = 240). The patient with the mixed infection including the E556G mutation was not included due to the lack of a PCt1/2 result. PC half-life: parasite clearance half-life; mixed WT: mixed wild type (presence of mutants and wild type); true WT: true wild type (no mutations at any of the tested loci)

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Malaria Journal

ISSN: 1475-2875

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