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Fig. 9 | Malaria Journal

Fig. 9

From: A randomized, double-blind, phase 2b study to investigate the efficacy, safety, tolerability and pharmacokinetics of a single-dose regimen of ferroquine with artefenomel in adults and children with uncomplicated Plasmodium falciparum malaria

Fig. 9

Estimated Day 7 concentrations of artefenomel and ferroquine in individual patients grouped by vomiting status and PCR-adjusted ACPR at Day 28 (African patients ≤ 5 years). All African patients ≤ 5 years with PCR-adjusted ACPR at Day 28 and exposure to both drugs were included (n = 231). The scatter plot displays the relationship between exposures to ferroquine (X axis) and artefenomel (Y axis) in African patients ≤ 5 years. Four quadrants were then defined according to the median artefenomel and ferroquine exposures, and the PCR-adjusted ACPR at Day 28 is provided for the patients belonging to each quadrant

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Malaria Journal

ISSN: 1475-2875

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