Fig. 4

Forest plot of polymerase chain reaction-corrected adequate clinical and parasite responses for studies with non- artemether–lumefantrine treatment arms. Among non-AL treatment arms including at least two studies, AS + AQ and AS + Pyr were the only treatment arms with pooled ACPRcs less than 100.0% (97.7% (95% CI 95.9%, 99.4%) and 97.6% (95% CI 92.7%, 100.0%), respectively. The overall ACPRc for non-AL treatment arms was 98.9% (95% CI 98.3%, 99.5%). Only treatment arms with at least two representative studies are shown. ACPRc: polymerase chain reaction-corrected adequate clinical and parasite response for falciparum malaria at 28 days; AL: artemether–lumefantrine; PCR: polymerase chain reaction