Fig. 2

Diagram of simulation model. Human hosts begin in a susceptible state and become Infected through contact with infectious mosquitoes. Infected human hosts may develop symptoms and seek treatment, which clears the infection and moves them to a protected state where they resist infection for 30 days. Susceptible human hosts may also enter the Protected state if they are given anti-malarial prophylaxis. Adult mosquitoes emerge at a constant rate and become infected through contact with infectious human hosts, and then become infectious after surviving through the extrinsic incubation period. Mosquitoes die at a constant rate. Not shown are human hosts moving between different patches and vaccination