Table 2 Results from Cox proportional hazard model analyses of time to parasite density less than 1000 per µl, adjusting for baseline parasite density, year and anti-malarial administered
Year | Number of subjects | Hazard ratio (95% CI) * | Hours to parasite reduction to < 1000 parasites/µl median (95% CI) | |
|---|---|---|---|---|
All quinine years | 2010–2013 | 30 (30,30) | ||
Individual years | 2010 | 118 | 0.34 (0.24, 0.48) | 30 (30,36) |
2011 | 68 | 0.46 (0.32, 0.68) | 30 (24,30) | |
2012 | 38 | 0.29 (0.18, 0.47) | 24 (18,36) | |
2013 | 35 | 0.57 (0.36, 0.90) | 24 (18,30) | |
All artesunate years | 2014–2019 | 18 (12,18) | ||
Individual years | 2014 | 53 | 1.00 | 18 (18,24) |
2015 | 30 | 1.36 (0.86, 2.17) | 18 (12,24) | |
2016 | 30 | 1.20 (0.76, 1.90) | 12 (12,18) | |
2017 | 45 | 1.25 (0.82, 1.89) | 18 (12,24) | |
2018 | 29 | 0.85 (0.53, 1.36) | 18 (12,24) | |
2019 | 19 | 0.95 (0.55, 1.63) | 15 (12,36) |