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Table 5 Univariate and multivariate associations of anaemia with asymptomatic malaria using microscopy, RDT, adjusted for age, sex and altitude

From: Prevalence of asymptomatic malaria, submicroscopic parasitaemia and anaemia in Korogwe District, north-eastern Tanzania

Variable

Unadjusted OR 95% CI

p-values

Model 1

P-values

Model 2

P-values

Adjusted OR, 95% CI

Adjusted OR, 95% CI

Asymptomatic based on microscopy

 Negative

Ref

 

Ref

–

–

–

 Positive

1.90 (0.90–4.0)

0.09

2.1 (1.0–4.5)

0.56

–

–

Age group (yr)

 < 5

Ref

 

Ref

 

Ref

 

 5–11

0.8 (0.5–1.3)

0.41

0.8 (0.5–1.2)

0.25

0.8 (0.5–1.2)

0.21

 12–14

0.6 (0.3–1.3)

0.20

0.6 (0.3–1.2)

0.13

0.6 (0.3–1.1)

0.11

 15–19

0.8 (0.4–1.5)

0.41

0.7 (0.4–1.5)

0.38

0.7 (0.4–1.4)

0.30

Sex

 Male

Ref

 

Ref

 

Ref

 

 Female

0.7 (0.5–1.0)*

 

0.7 (0.5–1.0)

0.53

1.0 (0.1–1.0)*

0.04

Altitude

 High

Ref

 

Ref

 

Ref

 

 Low

1.2 (0.8–1.7)

00.44

1.2 (0.8–1.8)

0.40

1.2 (0.8–1.7)

0.49

Asymptomatic based on RDT

 Negative

Ref

–

–

–

Ref

 

 Positive

1.9 (1.3–2.8)*

0.03

–

–

2.1 (1.3–3.2)*

0.01

  1. *p < 0.05, Model 1 included asymptomatic malaria based on microscopic results adjusted for gender, age and altitude whilst model 2 included asymptomatic malaria based on RDT adjusted for gender, age and altitude. The age groups presented here are as per the WHO haemoglobin concentrations for the diagnosis of anaemia and assessment of severity [17]