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Table 2 Frequency of polymorphisms in pfk13 gene in Plasmodium isolates in different geographical areas in Nigeria

From: Absence of Plasmodium falciparum artemisinin resistance gene mutations eleven years after the adoption of artemisinin-based combination therapy in Nigeria

Mutation

2004_Group A (n = 71)

2015 Group_B (n = 73)

2015 Group_C (n = 36)

Wild-type n (%)

Mutants n (%)

Wild-type n (%)

Mutants n (%)

Wild-type n (%)

Mutants n (%)

V510V

71 (100)

0 (0)

73 (100)

0 (0)

35 (97.2)

1 (2.8)

R515R

71 (100)

0 (0)

73 (100)

0 (0)

35 (97.2)

1 (2.8)

V520A

70 (98.6)

1 (1.4)

73 (100)

0 (0)

36 (100)

0 (0)

V581I

70 (98.6)

1 (1.4)

73 (100)

0 (0)

36 (100)

0 (0)

D547G

71 (100)

0 (0)

73 (100)

0 (0)

36 (97.2)

1 (2.8)

Q613Q

71 (100)

0 (0)

73 (100)

0 (0)

35 (97.2)

1 (2.8)

E688E

71 (100)

0 (0)

73 (100)

0 (0)

35 (97.2)

1 (2.8)

N458N

71 (100)

0 (0)

73 (100)

0 (0)

35 (92.2)

1 (2.8)

  1. Group A vs Group B (p = 0.4667), Group B Vs Group C ( p = 0.0070), Group A Vs Group C (p = 0.1319), Group A Vs Group B, Vs Group C ( p = 0.0052)