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Table 1 Association of MSP-1 genotyping with sequences diversities at the N-terminal and the central repeat regions of the Sudanese PfCSP genes

From: Assessment of genetic diversity of Plasmodium falciparum circumsporozoite protein in Sudan: the RTS,S leading malaria vaccine candidate

MSP-1 genotype

Sample origin

Presence of insertion in the N-terminal region of PfCSP

Total

P value

Number of NANP motif repeats

Total

P value

Yes

No

33

34

35

36

37

MAD20

Khartoum

6

–

6

0.428

–

–

6

–

–

6

0.787

Bahri

1

–

1

–

–

1

–

–

1

East Nile

1

–

1

–

–

1

–

–

1

Gebel Aulia

1

1

2

–

–

2

–

–

2

Karari

1

–

1

–

–

1

–

–

1

Omdurman

1

–

1

–

–

1

–

–

1

Umbada

1

–

1

–

–

1

–

–

1

K1

Khartoum

5

2

7

0.361

–

5

2

–

–

7

0.440

Bahri

2

–

2

–

–

2

–

–

2

Gebel Aulia

3

2

5

–

3

2

–

–

5

Karari

2

–

2

–

–

2

–

–

2

Omdurman

2

3

5

–

2

2

–

1

5

Umbada

3

–

3

–

1

2

–

–

3

RO33

Khartoum

4

6

10

0.358

–

4

2

2

2

10

0.763

Bahri

–

–

0

–

–

–

–

–

0

East Nile

5

1

6

2

1

1

–

2

6

Gebel Aulia

2

2

4

–

1

1

–

2

4

Karari

4

1

5

–

3

–

1

1

5

Omdurman

1

–

1

–

–

1

–

–

1

Umbada

1

2

3

1

–

1

–

1

3

Total

 

46

20

66

 

3

20

31

3

9

66

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